Primary Identifier | MGI:4361816 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Gfap-gp120)2Lms |
Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The env gene from the LAV strtain of HIV-1 was truncated to encode gp120 amino acids 1-509 and inserted in exon 1 of a modified murine Gfap gene. Five lines (2, 3,10, 16, 37) were established which varied in level of expression. Level of expression did not correlate with transgene copy number. This is a high expressor line. |