|  Help  |  About  |  Contact Us

Allele : Pole<tm1.1Bdp> polymerase (DNA directed), epsilon; targeted mutation 1.1, Bradley Preston

Primary Identifier  MGI:4366913 Allele Type  Targeted
Gene  Pole Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitution converted the aspartic acid at position 272 and glutamic acid at position 274 to alalnenes. These changes modify the exonuclease active site. The floxed neo cassette used for selection was removed by germ line, cre mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Pole<e>,
  • Pole<e>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele