Primary Identifier | MGI:4367784 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(PRNP-APPSweInd)19959Dwst |
Strain of Origin | 129S6/SvEvTac and FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene expresses the mutant human amyloid protein precursor APPSweInd, which bears both the Swedish (K670N/M671L) and the Indiana (V717F) mutations, under the control of the Syrian hamster prion protein promoter. |