Primary Identifier | MGI:6501795 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Col4a4 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The ENU-induced mutation was isolated in a screen looking for mice exhibiting end stage renal disease and was identified as a G to T change at position 1198 resulting in a glycine change to a stop codon at amino acid 400 (p.G400*). Immunofluorescence of kidneys confirmed absence of protein in glomeruli of homozygous mice. |