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Allele : Gldc<Gt(EUCG0001d02)Hmgu> glycine decarboxylase; gene trap EUCG0001d02, Helmholtz Zentrum Muenchen GmbH

Primary Identifier  MGI:4380899 Allele Type  Gene trapped
Attribute String  Hypomorph Gene  Gldc
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap vector consisting of long terminal repeats flanking a construct with pairs of FRT, F3, loxP and lox5171 sites surrounding a splice acceptor-neo-polyA cassette was inserted in intron 2. qRT-PCR analysis indicates that mRNA is diminished by 80-90% in homozygotes, indicating this is a strong hypomorphic allele.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Gldc<GT1>,
  • Gldc<GT1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele