Primary Identifier | MGI:4399144 | Allele Type | Targeted |
Attribute String | Inducible | Gene | Tcf3 |
Transmission | Germline | Strain of Origin | 129/Sv |
Induced With | tamoxifen | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The tamoxifen-responsive region from the mouse Esr1 gene with the G525R mutation was inserted at a modified STOP codon in Tcf3tm5Zhu replacing the GFP coding region. A neo cassette was also inserted for selection purposes. Both the E12 and E47 forms contain the modification resulting in tamoxifen-inducible function. |