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Allele : Tg(tetO-ATXN3)2904Olri transgene insertion 2904, Olaf Riess

Primary Identifier  MGI:4410556 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO-ATXN3)2904Olri
Strain of Origin  C57BL/6 Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The tetracycline response element was used to drive inducible expression of the human gene with 77 CAG repeats. Five lines were created (lines 2909, 2776, 2285, 2904, and 2723) with different transgene copy numbers and CAG repeats. Line 2904 contains three copies of the transgene with 60, 65, and 80 CAG repeats per copy. This line also exhibits the highest level of protein expression.
  • mutations:
  • Insertion
  • synonyms:
  • MJD77,
  • MJD77
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele