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Allele : Tg(SNCA)1Nbm transgene insertion 1, Robert L Nussbaum
Primary Identifier  MGI:4412055 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(SNCA)1Nbm
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  To generate the PAC-Tg(SNCAWT) transgene, the 146 kb RPCI-1 human male P1 artificial chromosome (PAC) clone 27M07, containing the entire human SNCA (synuclein, alpha (non A4 component of amyloid precursor)) gene and 34 kb of its upstream region, was used. This transgene was microinjected into the pronuclei of fertilized FVB/N ova. The only transgenic founder shown to contain the complete SNCA gene was bred to FVB/N wildtype mice.
  • mutations:
  • Insertion
  • synonyms:
  • PAC-Tg(SNCA<WT>),
  • hSNCA<WT>,
  • PAC-Tg(SNCA<WT>),
  • hSNCA<WT>
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1 Feature

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Genome

1 Expresses

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0 Mutation Involves

Phenotype

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