| Primary Identifier | MGI:4412048 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A construct containing a Thy1 promoter driving expression of the human APP with the Swedish familial Alzheimer disease mutations (K670N, M671L) was co-injected with a construct containing the Prnp promoter driving the expression of human PSEN2 with the familial Alzheimer disease mutation N141I. Line 152H was used in subsequent experiments. |
