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Allele : Hes1<tm1(cre/ERT2)Lcm> hes family bHLH transcription factor 1; targeted mutation 1, L Charles Murtaugh
Primary Identifier  MGI:4412375 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Hes1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting vector generated by bacterial recombineering replaced most of the Hes1 open reading from with a cre/ERT2 sequence linked to an Frt-flanked neomycin resistance cassette. Following homologous recombination in R1 ES cells, germline chimeras were generated and subsequently the neo cassette was excised in vivo by crossing mutants to Gt(ROSA)26Sortm1(FLP1)Dym mice.
  • mutations:
  • Insertion
  • synonyms:
  • Hes1<CF>,
  • Hes1<C2>,
  • Hes1<CreERT2>,
  • Hes1<CF>,
  • Hes1<CreERT2>,
  • Hes1<C2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

Trail: Allele

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Trail: Allele




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