Primary Identifier | MGI:4418115 | Allele Type | Targeted |
Attribute String | Knockdown, RMCE-ready | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The siRNA VsiR1 driven by the human U6 (RNU6) promoter was inserted into the locus using recombinase mediated cassette exchange (RMCE). Decreased expression of Trpv1 was confirmed by RT-PCR analysis and reduced protein expression was confirmed by a lack of receptor agonist binding. |