| Primary Identifier | MGI:4418524 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pdcd4 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An frt flanked neomycin cassette with a 5' attached loxP site was inserted in intron 3. An additional loxP site was inserted in intron 1. Exons 2 and 3 of the resulting allele are thus flanked by loxP sites. Mice were crossed to transgenic mice carrying a beta actin-cre to excise exons 2 and 3. This results in a frameshift mutation creating a stop site at codon 16. The resulting mice retain the frt flanked neomycin resistance cassette. |
