First Author | Vogel E | Year | 2016 |
Journal | Neuron | Volume | 91 |
Issue | 3 | Pages | 644-51 |
PubMed ID | 27497223 | Mgi Jnum | J:253917 |
Mgi Id | MGI:6109004 | Doi | 10.1016/j.neuron.2016.06.036 |
Citation | Vogel E, et al. (2016) Projection-Specific Dynamic Regulation of Inhibition in Amygdala Micro-Circuits. Neuron 91(3):644-51 |
abstractText | Cannabinoid receptor type 1 (CB1R)-expressing CCK interneurons are key regulators of cortical circuits. Here we report that retrograde endocannabinoid signaling and CB1R-mediated regulation of inhibitory synaptic transmission onto basal amygdala principal neurons strongly depend on principal neuron projection target. Projection-specific asymmetries in the regulation of local inhibitory micro-circuits may contribute to the selective activation of distinct amygdala output pathways during behavioral changes. |