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Allele : Foxp3<tm6.2Ayr> forkhead box P3; targeted mutation 6.2, Alexander Y Rudensky

Primary Identifier  MGI:4430233 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout, Reporter Gene  Foxp3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Two loxP sequences flanking conserved non-coding sequence 2 (CNS2 (Rr124)) in intron 1, as well as an FRT site flanked neomycin resistance gene cassette were inserted by homologous recombination. In addition, an EGFP cassette was inserted in-frame into the first coding exon. The selection cassette and the CNS were removed by flp- and cre-mediated recombination.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Foxp3<deltaCNS2gfp>,
  • Foxp3<deltaCNS2gfp>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele