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Allele : Trp53<tm6Xu> transformation related protein 53; targeted mutation 6, Yang Xu
Primary Identifier  MGI:4430743 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Trp53
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Leucine codon 25 (TTA) in exon 2 was changed to glutamine and tryptophan codon 26 (TTG) to serine (p.L25Q, p.W26S) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 4. The neo cassette was removed through subsequent Cre-mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • p53<QS-Neo>,
  • p53<Gln25Ser26>,
  • p53<QS-Neo>,
  • p53<Gln25Ser26>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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