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Allele : Ephb2<tm3.1Jf> Eph receptor B2; targeted mutation 3.1, Jonas Frisen

Primary Identifier  MGI:4431255 Allele Type  Targeted
Attribute String  Hypomorph Gene  Ephb2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A single nucleotide change was introduced within exon 12, resulting in amino acid substitution K661R, and a floxed neomycin phosphotransferase cassette was inserted within intron 11 by homologous recombination. This change is expected to disrupt the kinase activity. The selection cassette has been removed by cre mediated recombination.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Ephb2<K661R>,
  • Ephb2<K661R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele