| Primary Identifier | MGI:4437245 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase | Gene | Ret |
| Transmission | Germline | Strain of Origin | Not Specified |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The first exon of the Ret gene was targeted for homologous recombination. A sequence encoding inducible cre/ERT2, followed by a loxP-flanked AC-Cre Tn5-neo self-excising cassette, was targeted to exon 1 of Ret in ES cells. Following excision of the floxed neo cassette, a line of knockin mice expressing cre/ERT2 was generated. Spatial and temporal expression patterns of the inducible cre recapitulated Ret expression. |
