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Allele : Del(7Mrgpra1-Mrgprb4)1And deletion, Chr 7, David J Anderson 1
Primary Identifier  MGI:4436885 Allele Type  Targeted
Gene  Del(7Mrgpra1-Mrgprb4)1And Transmission  Germline
Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The coding exon of MrgprA1 was replaced with a self-excising neo cassette followed by a reverse tetracycline transactivator (rtTA), IRES sequence, and farnesylated EGFP. The coding exon was of MrgprB4 was replaced with a a hygro cassette, loxP site, and human placenta alkaline phosphatase coding sequence. Cre mediated recombination deletes the 845 kb sequence between the two targeted genes, which contains MrgprA10, A2, A14, A3, A12, A16, A19, A4, C11, B5, and 18 other genes.
  • mutations:
  • Intragenic deletion,
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Mrgpr-clusterdelta<->,
  • Del1And,
  • Mrgpr-clusterdelta<->,
  • Del1And
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1 Feature

Trail: Allele

Genome

0 Expresses

30 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

17 Publication categories

Trail: Allele




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