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Allele : Tg(Fabp4-LEP)F8Ffc transgene insertion F8, Farid F Chehab

Primary Identifier  MGI:4437889 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Fabp4-LEP)F8Ffc
Strain of Origin  C57BL/6J x DBA/2J Is Recombinase  false
Is Wild Type  false
molecularNote  The Fabp4-LEP transgene was designed with the mouse aP2 promoter driving the expression of the human leptin (LEP) gene. Fabp4-LEP consists of, from 5' to 3', an aP2 promoter/enhancer, rabbit beta-globin, human leptin cDNA, and human growth hormone (hGH) polyadenylation (polyA) signal. One line, F8, was generated. Expression of the transgene was detected in brown adipose tissue, all white adipose tissue depots and in macrophages.
  • mutations:
  • Insertion
  • synonyms:
  • LepTg,
  • LepTg
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele