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Allele : Rdh10<trex> retinol dehydrogenase 10 (all-trans); trex

Primary Identifier  MGI:4437845 Allele Type  Chemically induced (ENU)
Attribute String  Hypomorph Gene  Rdh10
Inheritance Mode  Recessive Strain of Origin  129S1/Sv or C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  ENU mutagenesis induced a T to C transition at nucleotide 251 (NM_133832) that results in the amino acid substitution of arginine for cystinine. This mutation is predicted to disrupt the first beta strand of the protein. Residual Retinoic Acid signaling is detected in the trunk neural tube indicating this is a severely hypomorphic allele.
  • mutations:
  • Single point mutation
  • synonyms:
  • trex,
  • trex
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories

Trail: Allele