Primary Identifier | MGI:4439131 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(H2-Ea-Cd74/MCC*T102E)29Nnak |
Strain of Origin | (C57BL/6 x SJL)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The H2-Ea promoter was used to control expression of a fusion protein composed of Cd74 (MHC II invarient chain) and sequence encoding amino acid residues 88-103 of moth cytochrome c. A mutation was created in the codon for amino acid residue 102 resulting in a threonine to glutamic acid substitution. |