| Primary Identifier | MGI:4440895 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Eno2-MFN2*R94Q)L51Ugfm |
| Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The MitoCharc1 transgene was designed with the human Mitofusin 2 (MNF2) gene driven by a rat enolase (Eno2) promoter. Amino acid 94 of MNF2 was mutated from an Arginine (R) to a Glutamine (Q) to mimic the most commonly mutated residue in Charcot-Marie-Tooth disease type 2A (CMT2A). Line L51 was established. |
