|  Help  |  About  |  Contact Us

Allele : Lrp5<tm1Mawa> low density lipoprotein receptor-related protein 5; targeted mutation 1, Matthew Warman

Primary Identifier  MGI:4453217 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Lrp5
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  lycine 170 of the targeted gene was converted to valine (equivalent to the human G171V missense mutation) via site-directed mutagenesis and a floxed neomycin selection cassette was placed in reverse transcriptional orientation in intron 2.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Lrp5 G171V-Neo,
  • Lrp5 G171V-Neo,
  • GN,
  • GN
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele