Primary Identifier | MGI:4454543 | Allele Type | Targeted |
Gene | Carm1 | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide substitution in exon 3 results in the amino acid substitution of arginine to alanine at position 169 (R169A). Exons 2 and 3 are also floxed. Flp mediated recombination removed the neo cassette upstream of exon 2. The predicted product is expected to be kinase dead. |