| Primary Identifier | MGI:4454647 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Cela1-IL1B)L123Tcw |
| Strain of Origin | CBA x C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The rat elastase promoter drives expression of the human interleukin-1beta gene. Expression of the transgene was confirmed in the pancreas by reverse-transcription (RT)-PCR and by enzyme-linked immunosorbent assay (ELISA) measurement of human IL-1beta peptide in pancreatic protein extracts. Expression was not detected in any of the other tissues analyzed, including liver, submaxillary glands, kidney, lung, and spleen. |
