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Allele : Tg(ACTB-BDNF)#Gdy transgene insertion, George Yancopoulos

Primary Identifier  MGI:4456441 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ACTB-BDNF)#Gdy
Strain of Origin  (CBA x C57BL/6)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  A human beta Actin promoter was used to drive expression of a human BDNF cDNA. Two founders carried two copies at a single integration site. Both lines were very similar so only one was maintained. Expression dropped between 8 weeks and 9 months of age.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele