| Primary Identifier | MGI:4457012 | Allele Type | Targeted |
| Gene | Trp53 | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This allele contains exon 4 of the human TRP53 gene, with the human proline variant at codon 72 (dbSNP:rs1042522; 72P). Codon 270, in the unmodified exon 8 - corresponding to human TRP53 codon 273 - encodes arginine (270R; mouse wild-type). A single loxP site in intron 1 is retained from an excised loxP-flanked translational STOP and selection cassette. |
