|  Help  |  About  |  Contact Us

Allele : Lmna<tm5Lgf> lamin A; targeted mutation 5, Loren G Fong

Primary Identifier  MGI:4457607 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lmna
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Introns 10 and 11 of Lmna were deleted thereby abolishing production of lamin C and producing a only non-farnesylated prelamin A. A point mutation was introduced into exon 12 that changes the cysteine of prelamin A's CaaX motif to a serine (i.e. CSIM to SSIM).
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Lmna<nPLAO>,
  • Lmna<nPLAO>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele