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Allele : Msh2<tm3.1Rak> mutS homolog 2; targeted mutation 3.1, Raju Kucherlapati

Primary Identifier  MGI:4460264 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Msh2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted upstream of modified exon 13 in which nucleotide substitutions (GGT to GAC) results in the amino acid substitution of aspartic acid for glycine at position 674 (G674D). Cre mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Msh2<G674D>,
  • Msh2<G674D>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele