Primary Identifier | MGI:4461396 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CAG-Map3k7*K63W)1232Mds |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of the chicken beta-actin promoter followed by a loxP flanked stop, a kinase-inactive Map3k7 with a K63W mutation, and a polyadenylation signal. Cre mediated recombination removes the stop and allows expression of the kinase-inactive Map3k7 gene. Map3k7 expression is increased about 4 fold and this is the highest expressing line. |