Primary Identifier | MGI:4462267 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Setdb1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre mediated recombination removed exon 16 and the beta-geo cassette. The reduction in protein production was confirmed by western blot analysis on Setdb1tm2.1Enl/Setdb1tm2.2 embryonic stem cells transfected with a cre-ERT2 plasmid and treated with tamoxifen. |