| Primary Identifier | MGI:4462407 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Ttr-Retn)1Laz |
| Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Three founder lines were established; line 1 is a representative line number. |
| molecularNote | This transgene consists of a mouse transthyretin (Ttr) minigene , which includes 3 kb of the Ttr promoter, the first and second exons of the Ttr gene, resistin (Retn) cDNA bearing the biologically active flag epitope at the 3' end and a polyA tail. Overexpression and quantification of Retn in white adipose tissue and liver was verified by northern blot, immunoblot (western) and radioimmunoassay. |
