Primary Identifier | MGI:4819117 | Allele Type | Chemically induced (ENU) |
Gene | Cd40lg | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | The mutation has been identified as a T to C transition at nucleotide position 673 of the transcript (NM_011616.2 from NCBI Build 37.1), in the last of the gene's 5 exons. It is predicted to result in replacement of serine by proline at amino acid position 221 of the protein, in the tumor necrosis factor (TNF)-like extracellular region. |