First Author | Seldin MF | Year | 1987 |
Journal | Immunogenetics | Volume | 26 |
Issue | 1-2 | Pages | 74-8 |
PubMed ID | 2886425 | Mgi Jnum | J:8805 |
Mgi Id | MGI:57270 | Doi | 10.1007/BF00345457 |
Citation | Seldin MF, et al. (1987) Allelic variants of Ly-5 in inbred and natural populations of mice. Immunogenetics 26(1-2):74-8 |
abstractText | Allelic variants of Ly-5 in inbred commensal and other natural populations of mice were analyzed by patterns of restriction fragment length polymorphisms (RFLP) and Southern hybridization using an Ly-5 cDNA probe and by cell-surface staining with a panel of antibodies directed against polymorphic and nonpolymorphic Ly-5 determinants. New Ly-5 alleles were defined by RFLPs generated by both Eco RI and Bam HI restriction enzyme digests. The Mus musculus subspecies and other species within the genus Mus showed a strong correlation between allelic variants defined by restriction enzymes and serologic specificities. The data also suggest the conservation of the Ly-5 gene throughout the genus Mus. |