Primary Identifier | MGI:4820570 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Ptk2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A lysine to arginine substitution at residue 454 (K454R) was introduced into exon 16 and a Neo cassette flanked by loxP sites was inserted into the upstream intron via homologous recombination. The Neo cassette was removed by Cre mediated recombination. |