Primary Identifier | MGI:4820740 | Allele Type | Transgenic |
Attribute String | Dominant negative, Humanized sequence, Inserted expressed sequence | Gene | Tg(ACTB-UPF1*R844C)581Hcd |
Strain of Origin | (C57BL/6 x 129)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human beta actin (ACTB) promoter drives expression of a dominant negative R844C mutant cDNA of the human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1) gene. Line 581 was generated. |