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Allele : Tg(ACTB-UPF1*R844C)581Hcd transgene insertion 581, Harry C Dietz

Primary Identifier  MGI:4820740 Allele Type  Transgenic
Attribute String  Dominant negative, Humanized sequence, Inserted expressed sequence Gene  Tg(ACTB-UPF1*R844C)581Hcd
Strain of Origin  (C57BL/6 x 129)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The human beta actin (ACTB) promoter drives expression of a dominant negative R844C mutant cDNA of the human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1) gene. Line 581 was generated.
  • mutations:
  • Insertion
  • synonyms:
  • RNT1 Dom Neg,
  • RNT1 Dom Neg
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele