| Primary Identifier | MGI:4822178 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | App |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neo resistance cassette was inserted 5' to exon 1 as well as an additional loxP site within intron 1 by homologous recombination. The neo cassette and exon 1 were removed by cre mediated recombination. Western blot analysis revealed the absence of any detectable protein expression. |