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Allele : Hfe<tm1.1Gfn> homeostatic iron regulator; targeted mutation 1.1, Susan Gilfillan
Primary Identifier  MGI:4821356 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hfe
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  2.5 kb of sequence containing the second and third exons, which encode the alpha1 and alpha2 putative ligand binding domains, were replaced with a floxed PGK neomycin selection cassette. Cre excision subsequently removed the neomycin selection cassette.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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