| Primary Identifier | MGI:4829505 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Jag2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT flanked PGKneo cassette and a distal loxP site were inserted into intron 2 and a second loxP site was inserted about 1.1 kb upstream of the start site via homologous recombination. Cre mediated recombination removed exons 1 and 2. In situ hybridization analysis indicated absence of RNA expression in E10.5 homozygous embryos. RT-PCR analysis detected low levels of expression in homozygous mice. |
