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Allele : Del(6Slco1b2-Slco1a5)1Nki deletion, Chr 6, the Netherlands Cancer Institute 1; deletion, Chr 6, The Netherlands Cancer Institute
Primary Identifier  MGI:4830091 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(6Slco1b2-Slco1a5)1Nki
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 and 4 of Slco1a5 were replaced with floxed neo cassette while exon 4 in Slco1b2 was replaced with a Pgk-thymidine kinase and floxed Pgk-hygro cassette. Cre mediated recombination remove the intervening sequence (including Gm5724, Slco1a4, Slco1a1, Gm6614, and Slco1a6). The absence of transcript expression was confirmed by RT-PCR on liver, kidney, and small intestine extracts.
  • mutations:
  • Intergenic deletion,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Del(6Slco1b2-Slco1a5)2Ahs,
  • Del1Nki,
  • Del1Nki,
  • Del(6Gm5724-Slco1a6)2Ahs,
  • Del(6Gm5724-Slco1a6)2Ahs,
  • Slco1a/1b<->,
  • Del(6)2Ahs,
  • Del(6)2Ahs,
  • Slco1a/1b<->,
  • Del(6Slco1b2-Slco1a5)2Ahs
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1 Feature

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13 Mutation Involves

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