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Allele : Cyp1a1<tm3.1Dwn> cytochrome P450, family 1, subfamily a, polypeptide 1; targeted mutation 3.1, Daniel W Nebert
Primary Identifier  MGI:4830523 Allele Type  Targeted
Gene  Cyp1a1 Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2 was replaced with a modified exon 2 in which the 93 bp coding for the SRP-binding and ER transmembrane anchor/stop transfer sequence was removed and Ala32 was replaced with a methionine (A32M). A floxed neo cassette inserted upstream of the modified exon was removed by cre mediated recombination. The product is predicted to undergo mitochondrial truncated targeting.
  • mutations:
  • Nucleotide substitutions,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cyp1a1<mtt>,
  • Cyp1a1<mtt>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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