| Primary Identifier | MGI:4830524 | Allele Type | Targeted |
| Gene | Cyp1a1 | Transmission | Germline |
| Strain of Origin | 129X1/SvJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 2 was replaced with a modified exon 2 in which nucleotide substitutions (CTT to AAT at codon 7 and CTC to AAC at codon 17) result in the amino acid substitutions of asparagine for leucine at positions 7 and 17 (L7N and L17N) in the SRP-binding and ER transmembrane anchor/stop transfer sequence. A floxed neo cassette inserted upstream of the modified exon was removed by cre mediated recombination. The product is predicted to undergo mitochondrial proteolysis targeting. |
