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Allele : Tg(LRRK2)66Mjff transgene insertion 66, The Michael J Fox Foundation

Primary Identifier  MGI:4834644 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(LRRK2)66Mjff
Strain of Origin  (C57BL/6 x SJL)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Bacterial artificial chromosome (BAC) library was used to obtain a BAC containing the entire human hLRRK2 (leucine-rich repeat kinase 2) gene. This BAC also contained a frt-flanked neomycin selection (neo) cassette which was removed by induction of an arabinose Flp-recombinase. Lines 41, 66, 70, and 107 were created. Transgene insertion occurred on Chr 6, causing a 756 bp deletion.
  • mutations:
  • Intergenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele