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Allele : Tg(Camk2a-AIDPak)21Stl transgene insertion 21, Susumu Tonegawa
Primary Identifier  MGI:4836192 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Camk2a-AIDPak)21Stl
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The dnPAK transgene was designed with the mouse autoinhibitory domain (AID) of the p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3) gene tagged with myc and driven by a mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a) promoter, followed by a simian virus 40 (SV40) polyadenylation site. This domain is conserved in all three Pak genes (Pak1, Pak2, Pak3). Lines 21 and 110 were generated.
  • mutations:
  • Insertion
  • synonyms:
  • dnPAK,
  • dnPAK
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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