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Allele : Sorcs1<tm1.1Gndy> sortilin-related VPS10 domain containing receptor 1; targeted mutation 1.1, Samuel Gandy

Primary Identifier  MGI:4836913 Allele Type  Targeted
Attribute String  Hypomorph Gene  Sorcs1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites flanking part of the promoter, all of exon 1, and a portion of intron 1 were introduced by homologous recombination. Cre mediated recombination removed exon 1 and the selection cassette. Mice exhibit a 50% reduction in transcript in brains.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele