Primary Identifier | MGI:4836913 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Sorcs1 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites flanking part of the promoter, all of exon 1, and a portion of intron 1 were introduced by homologous recombination. Cre mediated recombination removed exon 1 and the selection cassette. Mice exhibit a 50% reduction in transcript in brains. |