| Primary Identifier | MGI:4837530 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Tlr8 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | 2.3 kb of the coding sequence (amino acids 103-881) was replaced with a lacZ/neo cassette. RT-PCR and northern blot analysis confirmed the absence of transcript expression in unstimulated and LPS- or R848-stimulated bone marrow-derived dendritic cells. Beta galactose staining showed expression of lacZ in mutant lymph nodes and spleens. |
