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Allele : Wnk1<tm1.1Juha> WNK lysine deficient protein kinase 1; targeted mutation 1.1, Juliette Hadchouel

Primary Identifier  MGI:4838243 Allele Type  Targeted
Attribute String  Hypomorph, Modified isoform(s) Gene  Wnk1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4, an FRT site was inserted upstream of exon 4a, and a neo cassette flanked by attP and attB with 3' FRT and loxP site was inserted downstream of exon 4a. Flp mediated recombination removed the neo cassette and exon 4a. Exon 4 remains floxed. Real-time RT-PCR confirms the absence of the kidney specific transcript isoform.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • KS-WNK1<->,
  • KS-WNK1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele