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Allele : Cxcl12<tm3.1(HBEGF/EGFP)Tng> C-X-C motif chemokine ligand 12; targeted mutation 3.1, Takashi Nagasawa

Primary Identifier  MGI:4838646 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Reporter Gene  Cxcl12
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The coding region of exon 1 was replaced with human HBEGF (Diphtheria toxin receptor) fused to EGFP and a floxed neo cassette. Cre mediated recombination removed the neo cassette. This allele allows for conditional ablation of Cxcl12-expressing cells following treatment with Diphtheria toxin.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CXCL12-DTR-GFP,
  • CXCL12-DTR-GFP
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele