Primary Identifier | MGI:4838646 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Reporter | Gene | Cxcl12 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The coding region of exon 1 was replaced with human HBEGF (Diphtheria toxin receptor) fused to EGFP and a floxed neo cassette. Cre mediated recombination removed the neo cassette. This allele allows for conditional ablation of Cxcl12-expressing cells following treatment with Diphtheria toxin. |