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Allele : Tg(Emu-ETV6/JAK2)#Ghy transgene insertion, Jacques Ghysdael
Primary Identifier  MGI:4840013 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Emu-ETV6/JAK2)#Ghy
Strain of Origin  C57BL/6 x DBA/2 Is Recombinase  false
Is Wild Type  false
molecularNote  A cDNA encoding an HA-tagged version of the TEL-JAK2 protein encoded by a fusion gene, identified in a case of acute lymphoblastic T-cell leukemia, was inserted downstream of the Emu/SRalpha promoter/enhancer construct. The Emu/SRalpha enhancer/promoter allows high-level specific expression in lymphoid cells but only low to undetectable expression in nonlymphoid tissues.
  • mutations:
  • Insertion
  • synonyms:
  • EmuSRa-TEL-JAK2,
  • EmuSRa-TEL-JAK2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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