| Primary Identifier | MGI:4838863 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Epn3 |
| Transmission | Germline | Strain of Origin | C57BL/6J x 129S1/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert a loxP site upstream of the initiation site of the Epsin 3 (Epn3) gene. A frt-flanked neomycin resistance (neo) cassette, followed by a second loxP site, was placed downstream of exon 9. Cre mediated recombination deleted exons 1 through 9 and the neo. The absence of protein expression was confirmed by immunohistochemistry on parietal cells of the gastric glands. |